Neuroimaging

An empirical analysis of structural neuroimaging profiles in a staging model of depression

We examine structural brain characteristics across three diagnostic categories: at risk for serious mental illness; first-presenting episode and recurrent major depressive disorder (MDD). We investigate whether the three diagnostic groups display a …

Resting-state neural mechanisms of capability for suicide and their interaction with pain – A CAN-BIND-05 Study

Background: Suicidal ideation is highly prevalent in Major Depressive Disorder (MDD). However, the factors determining who will transition from ideation to attempt are not established. Emerging research points to suicide capability (SC), which …

Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report

This report from the CAN-BIND-1 study found that clinical response to the SSRI escitalopram was associated with clinical and neuroimaging correlates of reward processing.