Neurocognition

Neurocognitive Predictors of Response in Treatment Resistant Depression to Subcallosal Cingulate Gyrus Deep Brain Stimulation

This analysis aimed to (a) explore whether baseline cognitive measures could predict response to Deep Brain Stimulation (DBS) of the subcallosal cingulate gyrus for treatment-resistant depression (TRD), and (b) compare neurocognitive performance prior to and 12 months after DBS implantation. These preliminary results suggest that psychomotor speed may be a useful baseline predictor of SCG DBS treatment response, and support previous suggestions that SCG DBS has no deleterious effects on cognition.