Anhedonia

This report from the CAN-BIND-1 study found that clinical response to the SSRI escitalopram was associated with clinical and neuroimaging correlates of reward processing.

This literature review sought to elucidate the clinical and neurobiological differences in anhedonia and reward processing between MDD and schizophrenia, and explore the challenges and benefits of assessing anhedonia as a transdiagnostic feature under the Research Domain Criteria (RDoC) framework.